DetailsANXA7

Identification
Gene Name ANXA7
Accession Number HAMDB860
Molecular Type ion channel
Description Annexin A7
Synonyms ANXA7
Structure
Role in Autophagy
1 related item(s)

1. ANXA7
Gene Name ANXA7
Relationship with Autophagy increased activity of ANXA7 affects autophagy
Mutation Evidence wild type
Biomarker Application not applicable
Species Evidence Human
Drug Target Evidence not applicable
Expression evidence not applicable
Causal or Correlated causal
Findings 1
References
  1. Li H, Huang S, Wang S, Wang L, Qi L, Zhang Y, Zhang S, Zhao B, Miao J, Relationship Between Annexin A7 And Integrin β4 In Autophagy., Int J Biochem Cell Biol.2013 Nov;45(11):2605-11. Doi: 10.1016/j.biocel.2013.08.017. [PMID:24007983  ]
Biological Behaviors
Canonical Pathway
Not Available
Targeted By miRNA
  1. miR-106a-3p (and other miRNAs w/seed UGCAAUG)
  2. miR-10a-5p (and other miRNAs w/seed ACCCUGU)
  3. miR-1183 (miRNAs w/seed ACUGUAG)
  4. miR-124-3p (and other miRNAs w/seed AAGGCAC)
  5. miR-1252-5p (miRNAs w/seed GAAGGAA)
  6. miR-135a-5p (and other miRNAs w/seed AUGGCUU)
  7. miR-137-3p (and other miRNAs w/seed UAUUGCU)
  8. miR-195-3p (and other miRNAs w/seed CAAUAUU)
  9. miR-19b-3p (and other miRNAs w/seed GUGCAAA)
  10. miR-219a-5p (and other miRNAs w/seed GAUUGUC)
  11. miR-297a-5p (and other miRNAs w/seed UGUAUGU)
  12. miR-299a-5p (and other miRNAs w/seed GGUUUAC)
  13. miR-3119 (miRNAs w/seed GGCUUUU)
  14. miR-3149 (miRNAs w/seed UUGUAUG)
  15. miR-335-3p (miRNAs w/seed UUUUCAU)
  16. miR-3668 (miRNAs w/seed AUGUAGA)
  17. miR-3689a-5p (and other miRNAs w/seed GUGAUAU)
  18. miR-380-3p (and other miRNAs w/seed AUGUAGU)
  19. miR-3910 (miRNAs w/seed AAGGCAU)
  20. miR-3913-3p (miRNAs w/seed GACAUCA)
  21. miR-3923 (miRNAs w/seed ACUAGUA)
  22. miR-3925-5p (miRNAs w/seed AGAGAAC)
  23. miR-4289 (miRNAs w/seed CAUUGUG)
  24. miR-4317 (miRNAs w/seed CAUUGCC)
  25. miR-4491 (and other miRNAs w/seed AUGUGGA)
  26. miR-4672 (miRNAs w/seed UACACAG)
  27. miR-4679 (miRNAs w/seed CUGUGAU)
  28. miR-4693-5p (miRNAs w/seed UACUGUG)
  29. miR-4708-5p (miRNAs w/seed GAGAUGC)
  30. miR-4756-3p (miRNAs w/seed CAGAGAU)
  31. miR-489-3p (miRNAs w/seed UGACAUC)
  32. miR-508-3p (miRNAs w/seed GAUUGUA)
  33. miR-5186 (miRNAs w/seed GAGAUUG)
  34. miR-5585-3p (miRNAs w/seed UGAAUAG)
  35. miR-5624-3p (and other miRNAs w/seed UAAGGCA)
  36. miR-5691 (and other miRNAs w/seed UGCUCUG)
  37. miR-628-3p (miRNAs w/seed CUAGUAA)
  38. miR-6832-5p (miRNAs w/seed GUAGAGA)
  39. miR-7844-5p (miRNAs w/seed AAACUAG)
  40. miR-8070 (miRNAs w/seed UGUGAUU)
  41. miR-8075 (miRNAs w/seed GCUGAUG)
  42. miR-889-5p (miRNAs w/seed AUGGCUG)
Regulates
ITPR1; RAD23B; Ins1; NR3C1; NEUROD1; IGF1; PDX1; SLC2A2; PTEN; GSR; BCL2L2; CCNB1; HGF; IGHMBP2; GATA3
Regulated by
Ca2+; Pkc(s); SRC; GAST; AR-A014418; MMP14; fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether; CD40LG; lipopolysaccharide; CYP1A1; pirinixic acid; gemfibrozil; clofibrate; guanosine triphosphate; guanosine 5'-O-(3-thiotriphosphate)
Binds
SRI; ALG2; PDCD6; PAGA; ACEE; LLDD; AROC; FAN1; CD14; CEP135; CCDC88A; UBE2K; KIF11; DNAJC11; PPIA
Graphic indication
Role in cell
abnormal morphology; function; autophagy by; homeostasis in; proliferation; aggregation; fusion; breakage; adhesion; shrinkage
Disease
  1. intraventricular hemorrhage
  2. thrombocytosis
  3. lymphoid cancer
  4. lymphocytic cancer
  5. hematological neoplasia
  6. lymphatic neoplasia
  7. hematologic cancer
  8. weight gain
  9. digestive system cancer
  10. abdominal cancer
  11. liver neoplasia
  12. liver cancer
  13. cancer
  14. epithelial cancer
  15. epithelial neoplasia
  16. hyperplasia
  17. neoplasia
  18. lymphatic metastasis
  19. gigantism
  20. visceromegaly
  21. ventricular tachycardia
  22. atrial fibrillation
  23. tumorigenesis
Gene ID 310  
UniGene
GeneBank
RCSB PDB Not Available
DisProt Not Available
BioGrid 106807  
MINT MINT-4999305  
STRING 9606.ENSP00000362010  
ChEMBL Not Available
DrugBank
Not Available
Guide to PHARMACOLOGY Not Available
SwissLipids Not Available
BioMuta ANXA7  
Ensembl
KEGG hsa:310  
PharmGKB PA24835  
Reactome
Not Available
Gene wiki ANXA7  
References
  1. Li H, Huang S, Wang S, Wang L, Qi L, Zhang Y, Zhang S, Zhao B, Miao J, Relationship Between Annexin A7 And Integrin β4 In Autophagy., Int J Biochem Cell Biol.2013 Nov;45(11):2605-11. Doi: 10.1016/j.biocel.2013.08.017. [PMID:24007983  ]