841 Chemicals

796 Proteins

132 microRNA

e.g.,Chloroquine; 54-05-7    e.g.,AKT1; P31749    e.g., mir-10    e.g.,mk;   

What is HAMdb?

Autophagy is an important homeostatic cellular recycling mechanism which plays a key role in diverse pathologies. The goal of HAMdb is to provide the up-to-date information of existing autophagy-related modulators (proteins, chemicals and microRNA) including their specific effect on autophagy, pathway and disease information. Additionally, some basic information (structural and physicochemical information) and most commonly used links are also added to provide more details.

How to use?

HAMdb is easy to use for researchers. For chemical searching, general name, synonyms, trade names terms and CAS number can be used as an input (Example: search for Chloroquine, the following terms can be used: "Chloroquine", "Aralen" or "54-05-7"). A specific protein can query using gene name, synonyms, and uniport ID (Example: search for AKT1 can query using "AKT1" or "P31749"). As to microRNA, the general name can be used for searching (Example: mir-10 can be queried using "mir-10").

News & Updates

  • Version 2.4(2018-7-04). The disease information of ATG16L1 and ATG5 were added; The download method and the contact address were changed.
  • Version 2.3(2018-6-14). The display pattern of “Target by microRNA” and “Disease” were changed; The search function based on cell lines was added in the browse page.
  • Version 2.2(2018-6-14). Summary items of each modulator were deleted; Related interpretation of “Mutation evidence”, “Biomarker_Application”, “Species Evidence”, “Drug_target evidence”, “Expression evidence”, “Causal or Correlated” and “Role in cell” were added.
  • Version 2.1(2018-3-21). Related pathway, miRNA, upstream and downstream information of some proteins were supplemented.
  • Version 2.0(2017-8-23). Fixed bug.
  • Version 1.8(2017-8-09). physicochemical properties were calculated for chemicals.
  • Version 1.6(2017-6-17). detailed references and organism information of protein were added.
  • Version 1.4(2017-3-14). 841 autophagy-related chemicals and 11 microRNA were added.
  • Version 1.3(2016-9-10). 273 proteins with comprehensive information were added.
  • Version 1.2(2016-8-8). 523 proteins Information including 'Identification', 'Biological behaviors', ‘External links’ and autophagy information.
  • Version 1.0(2016-8-8). The HAMdb Version 1.0 was released.